Abstract: The article examines the trends and identifies the problems that hinder the effective operation of the enterprise, substantiates the need to develop new organizational-economic marketing-oriented forms of increasing the efficiency of their functioning, taking into account the conditions of market relations. The periodization of the development of marketing relations of domestic enterprises has been carried out, due to which the necessity of introducing a marketing mechanism for managing their activities, based on its sequential development as an integral system with a discrete state, represented by research, production, communication, sales and controlling subsystems, is argued. A prognostic-transformational model of the enterprise’s marketing mechanism was built, which takes into account the probabilistic nature of the impact of marketing processes on the economic state of the enterprise and a large list of factors influencing the enterprise’s marketing environment. The application of a complex approach to the evaluation of the effectiveness of the marketing mechanism of managing the company’s activities makes it possible to determine the effectiveness of its subordinate subsystems. The expediency of implementing a functional-regional organizational structure for managing the activities of enterprises is substantiated, based on the peculiarities of the placement of productive forces and the principles of their management. A scheme for making constructive management decisions has been developed according to a complex multivariate logistic model, which takes into account the degree of development, experience and financial stability of enterprises, as well as the most modern principles of production organization. For the stable functioning of enterprises in a hierarchical market environment, a transition to the concept of creating their positive image in a hierarchical market environment is proposed.